Successful long-term treatment of cerebral nocardiosis with unexpectedly low doses of linezolid in an immunocompromised patient receiving complex polytherapy.
نویسندگان
چکیده
Cerebral nocardiosis is a severe infection that carries the highest mortality rate among all bacterial cerebral abscesses. We report on a case in an immunocompromised patient which was successfully treated with unexpectedly low doses of linezolid. Therapeutic drug monitoring was very helpful in highlighting issues of poor compliance and of drug-drug interactions.
منابع مشابه
Primary Cutaneous Nocardiosis in a Patient With Nephrotic Syndrome
Nocardia infection is not common in clinical practice and most cases occur as an opportunistic infection in immunocompromised patients.We report a case of primary cutaneous nocardiosis characterized by multiple subcutaneous abscesses due to Nocardia brasiliensis in a patient with nephrotic syndrome undergoing long-term corticosteroid therapy. The patient was diagnosed with nephrotic syndrome 9 ...
متن کاملگزارش یک مورد نوکاردیوز مغزی در بیمار مبتلا به کرون
Introduction : Cerebral nocardiosis is a rare complication in patients who receive immunosuppressants, those with malignancy , AIDS, and transplant recipients. Case Report : Herein we present a case of Crohn’s disease who was being treated with prednisolone, salazine and azathioprine but suddenly faced a decrease in the level of consciousness and presented with the signs of focal neurologic...
متن کاملCombination antifungal therapy without craniotomy in an immunocompromised patient with rhino-orbito-cerebral mucormycosis: A case report
متن کامل
مقایسه کارآیی دو روش ایمونوفلورسانس غیر مستقیم و کشت آزمایشگاهی جهت تشخیص نوکاردیوز ریوی
Background: Pulmonary Nocardiosis is an infrequent infection whose incidence seems to be on the rise due to a higher degree of clinical suspicion and to an increasing number of immunosuppressive factors. The present investigation was carried out to detect Nocardiosis in immunocompromised patients confined in the pulmonary ward of Tehran’s Shariati Training Hospital through the use of indirect i...
متن کاملبررسی فراوانی ناهنجاریهای همراه در نوزادان مبتلا به آترزی مری بستری در بیمارستان حضرت علی اصغر(ع) از مهرماه سال 1384 تا1386
Introduction : Cerebral nocardiosis is a rare complication in patients who receive immunosuppressants, those with malignancy , AIDS, and transplant recipients. Case Report : Herein we present a case of Crohn’s disease who was being treated with prednisolone, salazine and azathioprine but suddenly faced a decrease in the level of consciousness and presented with the signs of focal neurologic...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 56 6 شماره
صفحات -
تاریخ انتشار 2012